USP7: NOVEL DRUG TARGET IN CANCER THERAPY

USP7: Novel Drug Target in Cancer Therapy

Ubiquitin specific protease 7 (USP7) is one of the deubiquitinating enzymes (DUB) that erases ubiquitin and protects substrate protein from degradation.Full activity of USP7 requires the C-terminal Ub-like domains fold back onto the catalytic domain, allowing the remodeling of the active Wall Sconce site to a catalytically competent state by the C-

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10-Hydroxy-2-Decenoic Acid in Royal Jelly Extract Induced Both Filaggrin and Amino Acid in a Cultured Human Three-Dimensional Epidermis Model

Royal jelly (RJ) is a natural product which the honeybee secretes as a special diet for a queen bee.It is one of the natural products in which various functionalities, such as antibacterial effects, immunomodulating properties, and estrogen-like action, were reported.We investigated Travel Mug the effect of the RJ extract on the moisturizing effect

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The detection of carbon dioxide leaks using quasi-tomographic laser absorption spectroscopy measurements in variable wind

Laser absorption spectroscopy (LAS) has been used over the last several decades for the measurement of trace gasses in the atmosphere.For over a decade, LAS measurements from multiple sources and tens of retroreflectors have been combined with sparse-sample tomography methods Wall Sconce to estimate the 2-D distribution of trace gas concentrations

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Presenting a Crisis Management Model with Emphasis on Human Resources Management System for Hospitals of Tehran

Crisis Management, as one of the key activities in strategic management has significant importance.One of the major requirements of crisis AC/DC Pins management is the high level of readiness and qualification of human resources responsible for crisis management.The focus of this paper is on presenting a crisis management model with human resources

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Application of a membrane condenser system for ammonia recovery from humid waste gaseous streams at a minimum energy consumption

Abstract Among the various technologies for the removal and recovery of chemicals from gaseous streams, the membrane condenser (MCo) is proposed and analyzed in this work.In particular, the case of MCo used Goalie - Skates - Junior for the recovery of ammonia at minimum energy consumption is reported.For reaching this aim, three different MCo confi

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